abstract：:The transient receptor potential cationic channel type A1 (TRPA1), belonging to a superfamily of cationic membrane channels, has been suggested to act as mechano- and pain sensor and, thus, to play a role in neurotransmission in the human body, including the urogenital tract. While the expression of TRPA1 has been inv...

journal_title：International journal of impotence research

authors： Ückert S,Sonnenberg JE,Albrecht K,Kuczyk MA,Hedlund P

更新日期：2015-01-01 00:00:00

abstract：:It is well known that the administration of phosphodiesterase type-5 inhibitors (PDE5-Is) may improve erectile function (EF) recovery after bilateral nerve-sparing radical prostatectomy (BNSRP). The aim of our study was to identify predictors of the use of a high number of PDE5-Is (one or more per week) after surgery ...

journal_title：International journal of impotence research

authors： Gandaglia G,Gallina A,Suardi N,Abdollah F,Passoni N,Bianchi M,Zaffuto E,Nini A,Vizziello D,Salonia A,Montorsi F,Briganti A

更新日期：2014-11-01 00:00:00

abstract：:This study was aimed to identify characteristics of ED patients who discontinued PDE5i despite successful intercourse. Data were collected using a questionnaire from 34 urologic clinics regardless of the effect (success or failure) of PDE5i treatment by visiting the clinics (717), e-mail (64) or post (101) for 882 ED ...

journal_title：International journal of impotence research

authors： Kim SC,Lee YS,Seo KK,Jung GW,Kim TH

更新日期：2014-05-01 00:00:00

abstract：:Erectile dysfunction (ED) develops owing to psychogenic, organic or/and both of these two factors. The aim of this study was to investigate the relationship between penile cavernosal arterial flow and peripheral atherosclerosis in men with ED. This study was conducted on 102 patients who had presented to Radiology Cli...

journal_title：International journal of impotence research

authors： Goksu C,Deveer M,Sivrioglu AK,Goksu P,Cucen B,Parlak S,Cetinkaya M,Altin L

更新日期：2014-03-01 00:00:00

abstract：:Unconsummated marriage (UM) is the failure to perform successful sexual intercourse at the beginning of the marriage. Vaginismus has been traditionally reported as the leading cause. ED is also a leading cause for UM. This appears to be a significant problem in the conservative middle-Eastern societies and in the deve...

journal_title：International journal of impotence research

authors： Michetti PM,Silvaggi M,Fabrizi A,Tartaglia N,Rossi R,Simonelli C

更新日期：2014-01-01 00:00:00

abstract：:Endothelial dysfunction, a marker for atherosclerosis and hence arterial disease, has recently been proffered as the main offender within the vascular system to predict not only the future onset of erectile dysfunction (ED) but also as the main cause of the ED. To glean more insight into whether arterial disease is in...

journal_title：International journal of impotence research

authors： Rajfer J,Valeriano J,Sinow R

更新日期：2013-11-01 00:00:00

abstract：:The Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) and its partner version questionnaire were used to assess couples' satisfaction with the use of phosphodiesterase type 5 (PDE5) inhibitors to treat erectile dysfunction (ED) over a 3-month period. Of 161 ED patients, who together with their female pa...

journal_title：International journal of impotence research

authors： Huang ST,Jiann BP

更新日期：2013-09-01 00:00:00

abstract：:To date, the effects of long-term testosterone (T) administration on the human vagina are not completely understood. Thus, the aim of this study was to investigate the effects of long-term T treatment on vaginal tissue histology, estrogen receptor alpha (ERα) and beta (ERβ) expression and proliferation in female to ma...

journal_title：International journal of impotence research

authors： Baldassarre M,Giannone FA,Foschini MP,Battaglia C,Busacchi P,Venturoli S,Meriggiola MC

更新日期：2013-09-01 00:00:00

abstract：:Cross-linked dextran and polymethylmethacrylate mixture (Lipen-10) is newly developed tissue filler. The purpose of this study was to evaluate tolerability and efficacy of Lipen-10 on penile enhancement. Twenty adult males were included in this study. Lipen-10 was injected into the subcutaneous tissue of the penile sh...

journal_title：International journal of impotence research

authors： Yang DY,Lee WK,Kim SC

更新日期：2013-05-01 00:00:00

abstract：:In erectile dysfunction (ED) research, monocultures of cavernous endothelial cells (CECs) and smooth muscle cells (CSMCs) have been reported, but a CEC-CSMC coculture system is still lacking. In the present study, we wished to investigate the feasibility of setting up such a system and test whether it can be used for ...

journal_title：International journal of impotence research

authors： Ning H,Lin G,Lue TF,Lin CS

更新日期：2013-03-01 00:00:00

abstract：:The activation of cavernous local renin-angiotensin system has an important role in pathogenesis of diabetic erectile dysfunction (ED). In our primary study, we found that angiotensin Type 1 receptor blocker improved the erectile function of diabetic rats. Therefore we explored the losartan in clinical treatment for d...

journal_title：International journal of impotence research

authors： Chen Y,Cui S,Lin H,Xu Z,Zhu W,Shi L,Yang R,Wang R,Dai Y

更新日期：2012-11-01 00:00:00

abstract：:Premature ejaculation (PE), the most common sexual dysfunctions in men, is characterized by loss or absence of ejaculatory control. PE can be classified as either a lifelong or acquired condition. Although the prevalence of lifelong PE is rather low in the general male population, recent studies demonstrated that the ...

journal_title：International journal of impotence research

authors： Koyuncu H,Serefoglu EC,Ozdemir AT,Hellstrom WJ

更新日期：2012-09-01 00:00:00

abstract：:Non-surgical treatment of Peyronie's disease (PD) has come a long way since it was first described in 1743. A myriad of treatment options are currently available, including oral, intralesional and external energy therapies. The purpose of this article is to review the contemporary literature on non-surgical therapies ...

journal_title：International journal of impotence research

authors： Larsen SM,Levine LA

更新日期：2012-01-01 00:00:00

abstract：:Radical prostatectomy (RP) is a commonly performed procedure for the management of prostate cancer. While documented oncologic outcome for early stage disease is excellent, functional impairments such as incontinence and erectile dysfunction (ED) are common after the procedure. Recent evidence has implicated cavernous...

journal_title：International journal of impotence research

authors： Moskovic DJ,Miles BJ,Lipshultz LI,Khera M

更新日期：2011-09-01 00:00:00

abstract：:There is strong evidence from multiple epidemological studies that lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) are correlated, independent of age or comorbidities as diabetes or hypertension. Although a direct causal relationship is not established yet, four pathophysiological mechanisms can expl...

journal_title：International journal of impotence research

authors： Orabi H,Albersen M,Lue TF

更新日期：2011-05-01 00:00:00

abstract：:The relation between coronary artery ectasia (CAE) and erectile dysfunction (ED) has not been studied so far. Hence, we decided to investigate the erectile function score in patients with CAE. We investigated the international index of erectile function (IIEF)-5 score in 34 men with CAE, 38 men with coronary artery di...

journal_title：International journal of impotence research

authors： Akcay AB,Inci M,Bilen P,Acele A,Sen N,Yalcin F

更新日期：2011-05-01 00:00:00

abstract：:No oral medication has proved to be clearly beneficial for Peyronie's disease (PD). We investigated the safety and efficacy of coenzyme Q(10) (CoQ(10)) supplementation in patients with early chronic PD. We conducted a randomized clinical trial of 186 patients with chronic early PD. Patients were randomly assigned to e...

journal_title：International journal of impotence research

authors： Safarinejad MR

更新日期：2010-09-01 00:00:00

abstract：:The aims of this study were to investigate the prevalence of ED in Chinese men with type 2 diabetes mellitus, and evaluate the efficacy and safety of sildenafil citrate in these patients. Patients from 42 outpatient diabetes clinics with type 2 diabetes mellitus and ED as defined by the International Index of Erectile...

journal_title：International journal of impotence research

authors： Yang G,Pan C,Lu J

更新日期：2010-09-01 00:00:00

abstract：:Both overweight and obesity have been identified as risk factors for sexual dysfunction in men, but the relationship between sexual function and amount of body fat in females is still obscure. There are few reported studies in women assessing the relationship between female sexual function index (FSFI) and body weight...

journal_title：International journal of impotence research

authors： Yaylali GF,Tekekoglu S,Akin F

更新日期：2010-07-01 00:00:00

abstract：:This work aimed to assess the cavernous anti-apoptotic role of using chronic low-dose sildenafil/tadalafil with and without testosterone (T) in aged diabetic rats. In all, 140 Sprague-Dawley aged rats were divided into the following groups: controls; induced diabetic rats; diabetic rats that received intramuscular dep...

journal_title：International journal of impotence research

authors： Mostafa T,Rashed LA,Kotb K

更新日期：2010-07-01 00:00:00

abstract：:End-stage renal disease (ESRD) affects sexual function. The etiology of sexual dysfunction in ESRD is multifactorial and hypogonadism is not uncommon. In a cohort of 96 men with ESRD, scores on International Index of Erectile Function (IIEF) correlated with bioavailable testosterone (T; P<0.01). We further evaluated t...

journal_title：International journal of impotence research

authors： Cangüven O,Aykose G,Albayrak S,Goktas C,Horuz R,Yencilek F

更新日期：2010-03-01 00:00:00

abstract：:Erectile dysfunction (ED) is linked to various cardiovascular risk factors and may therefore serve as a predictor of cardiovascular events. To gain further insight into this relationship, we reviewed all data regarding hospital admission for cardial or cerebral vascular disease that occurred until 2008 in a cohort of ...

journal_title：International journal of impotence research

authors： Ponholzer A,Gutjahr G,Temml C,Madersbacher S

更新日期：2010-01-01 00:00:00

abstract：:Defining the minimal clinically meaningful improvement (MCMI) is crucial to understanding the treatment effects on health-status measures. We estimated the MCMI on the quality of erection questionnaire (QEQ), a validated measure specific to assess erectile quality during sexual intercourse. Data were from two controll...

journal_title：International journal of impotence research

authors： Hvidsten K,Carlsson M,Stecher VJ,Symonds T,Levinson I

更新日期：2010-01-01 00:00:00

abstract：:One of the most commonly used tests to distinguish psychogenic from organic erectile dysfunction (ED) is to monitor nocturnal penile tumescence using the RigiScan device and its new software called RigiScan Plus. To give a true estimate of the predictive ability of the new RigiScan software parameters, tumescence acti...

journal_title：International journal of impotence research

authors： Elhanbly S,Elkholy A,Elbayomy Y,Elsaid M,Abdel-gaber S

更新日期：2009-11-01 00:00:00

abstract：:The objective of this study was to determine the cardiovascular risk factors among men with erectile dysfunction (ED) at a hospital-based primary care clinic in Riyadh, Saudi Arabia. A cross-sectional study was conducted at a primary care clinic in the King Khalid University Hospital (Riyadh, Saudi Arabia), during the...

journal_title：International journal of impotence research

authors： Abdulah Al Turki Y

更新日期：2009-11-01 00:00:00

abstract：:Using our prospectively derived database, we identified 17 patients with squamous-cell carcinoma involving the glans penis, who were treated using organ-sparing surgery between March 2003 and January 2008. Of them, two were treated with partial glansectomy with primary glans closure, and 15 underwent total glans amput...

journal_title：International journal of impotence research

authors： Morelli G,Pagni R,Mariani C,Campo G,Menchini-Fabris F,Minervini R,Minervini A

更新日期：2009-09-01 00:00:00

abstract：:We studied the association between erythrocyte aggregation (EA) and erectile dysfunction (ED) in men with coronary artery disease (CAD). Men with CAD documented by coronary angiography filled the Sexual Health Inventory for Males questionnaire to detect ED and assess its severity. EA was evaluated by filming slides of...

journal_title：International journal of impotence research

authors： Justo D,Mashav N,Arbel Y,Kinori M,Steinvil A,Swartzon M,Molat B,Halkin A,Finkelstein A,Heruti R,Banai S

更新日期：2009-05-01 00:00:00

abstract：:The sexuality and the management of benign prostatic hyperplasia (BPH) with alfuzosin (SAMBA) trial evaluated the effect of alfuzosin on sexual function in men treated for BPH using two sexual function scales: male sexual health questionnaire (MSHQ) and international index of erectile function (IIEF-15). A total of 14...

journal_title：International journal of impotence research

authors： Chung BH,Lee JY,Kim CI,Kim CS,Oh CY,Lee SW,Lee JS,Yoo SJ

更新日期：2009-01-01 00:00:00

abstract：:Several analyses have demonstrated a clinically useful relationship between serum prostate specific antigen (PSA) and prostate volume in men with benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Both prostate volume and serum PSA predict certain aspects of the natural history of LUTS and BPH...

journal_title：International journal of impotence research

authors： Roehrborn CG

更新日期：2008-12-01 00:00:00

abstract：:The authors created the glans penis augmentation by injectable hyaluronic acid gel and reported the 6-month result for premature ejaculation. In a total of 38 patients, long-term effects of 5 years were compared to those of 6 months in terms of residual volume of implants and efficacy on premature ejaculation. Maximal...

journal_title：International journal of impotence research

authors： Kwak TI,Jin MH,Kim JJ,Moon DG

更新日期：2008-07-01 00:00:00

abstract：:Although decline in sexual function is a common reason for ageing men to seek advice regarding testosterone therapy, placebo-controlled trial data have been unable to show a consistent, beneficial role for testosterone. The objective of this study was to determine the effect of testosterone therapy on sexual function ...

journal_title：International journal of impotence research

authors： Allan CA,Forbes EA,Strauss BJ,McLachlan RI

更新日期：2008-07-01 00:00:00

abstract：:Currently available agents for erectile dysfunction (ED) share the same mechanism of action and pharmacologic properties. Therefore, they share the same limitations, including a principal focus on erection as an end-organ process. One of the relatively unexplored areas of research has been the potential for centrally ...

journal_title：International journal of impotence research

authors： Hellstrom WJ

更新日期：2008-07-01 00:00:00

abstract：:In an observational study in men with erectile dysfunction (ED) consulting a general practitioner (GP) or urologist in Belgium, demographics, ED characteristics (including erection hardness score), co-morbidities and treatment expectations were evaluated using a structured questionnaire. In total, 341 GPs and 41 urolo...

journal_title：International journal of impotence research

authors： Claes H,Opsomer RJ,Andrianne R,Vanbelle S,Albert A,Vanderdonck F

更新日期：2008-07-01 00:00:00

abstract：:Soluble guanylyl cyclase (sGC) is the major effector molecule for nitric oxide (NO) and as such an interesting therapeutic target for the treatment of erectile dysfunction. To assess the functional importance of the sGCalpha(1)beta(1) isoform in corpus cavernosum (CC) relaxation, CC from male sGCalpha(1)(-/-) and wild...

journal_title：International journal of impotence research

authors： Nimmegeers S,Sips P,Buys E,Decaluwé K,Brouckaert P,Van de Voorde J

更新日期：2008-05-01 00:00:00

abstract：:The study objective was to evaluate the efficacy of changing testosterone gel preparations among suboptimally responsive hypogonadal men. The records of all hypogonadal men on gel (Testim or Androgel) testosterone replacement therapy (TRT) were reviewed to identify men who underwent a brand substitution in gel TRT due...

journal_title：International journal of impotence research

authors： Grober ED,Khera M,Soni SD,Espinoza MG,Lipshultz LI

更新日期：2008-03-01 00:00:00

abstract：:We investigated whether coronary flow reserve (CFR) can be modified by tadalafil, a long-acting phosphodiesterase 5 (PDE5) inhibitor, in patients with documented coronary artery disease (CAD). CFR was non-invasively evaluated in 12 men with a positive history for erectile dysfunction (ED) and angiographically document...

journal_title：International journal of impotence research

authors： Bellotto F,Ruscazio M,Bonanni G,Montisci R,Cutolo A,Sarais C,Setzu T,Borrini A,Iliceto S

更新日期：2008-03-01 00:00:00

abstract：:The Hypogonadism In Males study estimated the prevalence of hypogonadism in men aged > or =45 years. A sub-analysis of patients not receiving testosterone (T) therapy was conducted. Blood draw times were 0800-1000 and 1000-1200 hours. Total T (TT) was not influenced by draw time for any age group; however, significant...

journal_title：International journal of impotence research

authors： Guay A,Miller MG,McWhirter CL

更新日期：2008-03-01 00:00:00

abstract：:Sexual dysfunction is a common problem of increasing incidence that is associated with multiple co-morbid conditions and chronic diseases. In heart failure, however, exact numbers are unknown, in part secondary to under-reporting and under-interrogating by health care providers. A gender-specific questionnaire was mod...

journal_title：International journal of impotence research

authors： Schwarz ER,Kapur V,Bionat S,Rastogi S,Gupta R,Rosanio S

更新日期：2008-01-01 00:00:00

abstract：:Apprehension about the normal size of penis is a major concern for men. Aim of the present investigation is to estimate the penile length and circumference of Indian males and to compare the results with the data from other countries. Results will help in counseling the patients worried about the penile size and seeki...

journal_title：International journal of impotence research

authors： Promodu K,Shanmughadas KV,Bhat S,Nair KR

更新日期：2007-11-01 00:00:00

abstract：:Modulation of the adrenergic activity and interfering with channels such as potassium channels may affect relaxation and contraction of the corpus cavernosum. Sildenafil is a selective phosphodiesterase-5 inhibitor, proven effective in treating erectile dysfunction. In this study, the effect of sildenafil citrate on a...

journal_title：International journal of impotence research

authors： El-Metwally MA,Sharabi FM,Daabees TT,Senbel AM,Mostafa T

更新日期：2007-11-01 00:00:00